bacon - Controlling bias and inflation in association studies using the empirical null distribution
Bacon can be used to remove inflation and bias often observed in epigenome- and transcriptome-wide association studies. To this end bacon constructs an empirical null distribution using a Gibbs Sampling algorithm by fitting a three-component normal mixture on z-scores.
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immunooncologystatisticalmethodbayesianregressiongenomewideassociationtranscriptomicsrnaseqmethylationarraybatcheffectmultiplecomparison
3.90 score 1 scripts 632 downloadsTurboNorm - A fast scatterplot smoother suitable for microarray normalization
A fast scatterplot smoother based on B-splines with second-order difference penalty. Functions for microarray normalization of single-colour data i.e. Affymetrix/Illumina and two-colour data supplied as marray MarrayRaw-objects or limma RGList-objects are available.
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microarrayonechanneltwochannelpreprocessingdnamethylationcpgislandmethylationarraynormalization
3.30 score 3 scripts 658 downloadsMethylAidData - MethylAid-summarized data for 2800 Illumina 450k array samples and 2620 EPIC array samples
A data package containing summarized Illumina 450k array data on 2800 samples and summarized EPIC data for 2620 samples. The data can be use as a background data set in the interactive application.
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experimentdatatechnologydatamicroarraydatamethylationarraydatadatapkg
3.30 score 3 scripts